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LOCATION:Online
DESCRIPTION:This presentation is dedicated to the modification of the Biginelli reaction for the synthesis of trisubstituted imidazoles from readily available acyclic N\, N-bis-nucleophiles\, 2-oxoaldehydes and 1\,3-dicarbonyl compounds. Most of the synthesized products were successfully used in the subsequent photocyclization reaction to form structurally interesting polycyclic molecules. The replacement of N\, N-bis-nucleophiles to ketenaminals allowed to carry out a similar process in a chemoselective manner to obtain a diverse library of fused polyheterocycles including pyrrolo[2\,1-b]thiazoles\, pyrrolo[1\,2-a]imidazoles and imidazo[1\,2-a] quinolines.
DTSTART:20231220T163000Z
DTEND:20231220T173000Z
SUMMARY:Seminar “Modifications of the Biginelli reaction for the synthesis of various nitrogen-containing heterocycles”
URL;VALUE=URI:/media/events/seminar-modifications-of-the-biginelli-reaction-for-the-synthesis-of-various-nitrogen-containing-heterocycles/
DTSTAMP:20250430T045612Z
UID:6811833cf2e8d
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