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The history of the "Perftoran" must be continued

The history of the "Perftoran" must be continued

At the end of the last century, Soviet scientists proposed the drug “Perftoran” as a blood substitute, which today could safely be called innovative. Created on the basis of perfluorocarbon compounds, it could compensate for the lack of oxygen in the patient’s body due to the absorption mechanism of its transfer. However, the composition, unofficially named for the color “blue blood”, revealed certain shortcomings, which the authors were not able to eliminate at the time. We could not do it abroad.

Employees of the center for collective use (Scientific and educational center) of the Russian Academy of Sciences took up this difficult task. The reason for this was the developing COVID-19 pandemic in the world.

It is known that oxygen deficiency affects the severity of ischemic brain and heart damage, shock and collapse states, infectious and non-infectious diseases, the formation of multiple organ failure and stressful situations.

The research team led by the Director of the center for biotechnology and synthesis of Common Use Center (Research and Educational Center) of RUDN University Arkady Khromov formed a new algorithm for obtaining perfluorocarbon blood substitutes with nanoscale emulsion particles, which will ensure its low viscosity and oxygen delivery to the final link of the systemic blood flow — the capillary. The developers also know how to make the infusion drug stable during its long-term storage without freezing.

To implement the project, funding is required. To date, an application for a grant from the Russian Foundation for basic research (RFBR) on the topic “Fundamental research on the development of drugs based on perfluorocarbon compounds for the delivery of oxygen to the body tissues of a patient infected with coronavirus” has been issued.

We wish our colleagues good luck in achieving this goal.

International Projects View all
Main Publications View all
15 Nov 2017
RUDN University scientists publish results of their scientific researches in highly-recognized in whole world and indexed in international databases journals (Web of Science, Scopus ect.). That, of course, corresponds to the high status of the University and its international recognition. Publications of June-September 2017 ( In Journals of categories Q1-Q3)
2018
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20 Apr
A volunteer of the Red Army and head of the veterinary medicine course — Matilda Mityaeva's combat and scientific path

Matilda Pavlovna Mityaeva was born in 1925. In November 1942, she volunteered for frontline duty. She participated in the Great Patriotic War from November 1942 to June 1945 as part of the 53rd Infantry Division of the 475th Infantry Regiment. She was wounded twice.

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20 Apr
RUDN University Team – the 1st place in the all-russian competitive selection of scientific projects “Technologies for human health”

The team led by Sergey Zyryanov, Head of the Department of General and Clinical Pharmacology, became the winner of the All-Russian competition of scientific projects "Technologies for Human Health".

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20 Apr
RUDN University Scientific Agenda to 2030: New Programme for R&D and Innovation Activities Development

RUDN University constantly adapts to the changes of the modern world and responds to challenges flexibly. This allows us to keep the standard of a world-class research university. The sphere of science is no exception. Peter Dokukin, Head of the Research Division, presented the updated R&D Programme at the meeting of the RUDN University Academic Council.

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